- Recommended name
- Gymnodimine-B
- Synonyms
- Gymnodimine B
- Recommended acronym
- GYM-B
- Abbreviation
Progenitors
- Name
- Karenia selliformis
- Note
- Miles et al., 2000
Vector Species
- Name
- Ruditapes decussatus
- Note
- Kharrat et al.,2008
References
- Christopher O. Miles, 2000
- Miles, C. O., Wilkins, A. L., Stirling, D. J., & MacKenzie, A. L. (2000). New analogue of gymnodimine from a Gymnodinium species. Journal of Agricultural and Food Chemistry, 48(4), 1373-1376.
- Riadh Kharrat, 2008
- Kharrat, R., Servent, D., Girard, E., Ouanounou, G., Amar, M., Marrouchi, R., ... & Molgó, J. (2008). The marine phycotoxin gymnodimine targets muscular and neuronal nicotinic acetylcholine receptor subtypes with high affinity. Journal of neurochemistry, 107(4), 952-963.
- Idriss Ben Naila, 2012
- Naila, I. B., Hamza, A., Gdoura, R., Diogene, J., & de la Iglesia, P. (2012). Prevalence and persistence of gymnodimines in clams from the Gulf of Gabes (Tunisia) studied by mouse bioassay and LC–MS/MS. Harmful Algae, 18, 56-64.
- Structure
- Formula
- C32H45NO5
- Exact mono-isotopic mass
- 523.714
- Molfile
- n/a
- Alternative molfiles
- n/a
- SMILES
- CC1CC2CCC(C(=CC3C(=C(CCC34CCCN=C4CCC(C(=C)C1O2)O)C5C=C(C(=O)O5)C)C)C)O
- Alternative SMILES
- C[C@@H]1C[C@@H]2CC[C@@H](/C(=C/[C@H]3C(=C(CC[C@@]34CCCN=C4CC[C@@H](C(=C)[C@H]1O2)O)[C@@H]5C=C(C(=O)O5)C)C)/C)O
- InChi key
- QVXVRMLMEOIRPY-UFQMMXIBSA-N
- Alternative InChi keys
- n/a
- InChi
- InChI=1S/C32H45NO5/c1-18-16-25-21(4)24(28-17-20(3)31(36)38-28)11-13-32(25)12-6-14-33-29(32)10-9-27(35)22(5)30-19(2)15-23(37-30)7-8-26(18)34/h16-17,19,23,25-28,30,34-35H,5-15H2,1-4H3/b18-16+/t19-,23+,25+,26+,27+,28+,30+,32+/m1/s1
- Alternative InChis
- Spectra available
- Unknown
- Chem files
References
- Christopher O. Miles, 2000
- Miles, C. O., Wilkins, A. L., Stirling, D. J., & MacKenzie, A. L. (2000). New analogue of gymnodimine from a Gymnodinium species. Journal of Agricultural and Food Chemistry, 48(4), 1373-1376.
- Certified
- False
- Certified links
-
-
n/a
- Non certified reference material
- Unknown
Chemical analysis
- Research
- True
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
Structure recognition assays
- Research
- Unknown
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
Functional assays
- Research
- Unknown
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
Animal assays
- Research
- Unknown
- Standardized
- Unknown
- Validated
- Unknown
- Official
- n/a
References
- Idriss Ben Naila, 2012
- Naila, I. B., Hamza, A., Gdoura, R., Diogene, J., & de la Iglesia, P. (2012). Prevalence and persistence of gymnodimines in clams from the Gulf of Gabes (Tunisia) studied by mouse bioassay and LC–MS/MS. Harmful Algae, 18, 56-64.
- Regulatory status
- False
- Human toxic syndrome(s)
- n/a
- Organ system toxicity
- n/a
- Risk assessment
- Unknown
- Molecular targets known
- Unknown
- Molecular targets
- n/a
- Toxic to aquatic animals
- Unknown
- TEF available
- True
TEF References
- Riadh Kharrat, 2008
- Kharrat, R., Servent, D., Girard, E., Ouanounou, G., Amar, M., Marrouchi, R., ... & Molgó, J. (2008). The marine phycotoxin gymnodimine targets muscular and neuronal nicotinic acetylcholine receptor subtypes with high affinity. Journal of neurochemistry, 107(4), 952-963.
- Notes
- The total amount of GYMs equivalents was calculated with a toxicity equivalent factor (TEF) of 0.1 for GYM-B/C (Kharrat et al., 2008).
- Aifeng Li
- Contact